貨號 | 品牌 | CAS | 規格 | 銷(xiāo)售價(jià)(RMB) | 折扣價(jià)(RMB) | 備注 | 數量 |
ABP50881-100 μL | Abbkine | 無(wú) | 100μL | 1616 | 1616 | 無(wú) | |
ABP50881-30μL | Abbkine | 無(wú) | 30μL | 739 | 739 | 無(wú) | |
ABP50881-100μL | Abbkine | 無(wú) | 100μL | 1616 | 1616 | 無(wú) |
產(chǎn)品英文名稱(chēng) | CBP Polyclonal Antibody |
免疫原 | 合成多肽:來(lái)源于C端的人源蛋白CBP. 氨基酸序列為: 2370-2450 |
宿主 | 兔 |
反應性 | 人, 小鼠 |
應用 | ELISA, IF, IHC-P, WB |
實(shí)驗建議 | 最佳的工作稀釋比例需要客戶(hù)摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:500-1:2000,IHC-p:1:100-1:300,IF:1:200-1:1000,ELISA:1:10000。 尚未在其他應用中測試。 |
克隆性 | 多克隆 |
純化工藝 | 使用表位特異性的免疫原,通過(guò)親和層析,從兔抗血清中親和純化抗體。 |
產(chǎn)品形式 | 液體溶液 |
濃度 | 1 mg/ml |
儲存緩沖液 | 含有50%甘油,0.5%BSA和0.02%疊氮化鈉的PBS緩沖液。 |
保存建議 | 自發(fā)貨之日起,-20°C可穩定保存1年。為最大限度的避免損失,請在打開(kāi)管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復凍融。 |
運輸條件 | 藍冰運輸 |
警告 | 本文列出的產(chǎn)品僅供研究使用,不適用于人類(lèi)或臨床診斷。我們產(chǎn)品所推薦應用,不是建議使用我們的產(chǎn)品去違反任何專(zhuān)利或許可證。對于使用本產(chǎn)品可能發(fā)生的專(zhuān)利侵權或其他違規行為,我們不承擔任何責任。 |
背景 | CREBBP is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB, CREBBP is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREB binding protein has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. CREB binding protein acetylates both histone and non-histone proteins. CREB binding protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in CREBBP cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving CREBBP have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
基因ID | 1387 |
別名 | CREBBP; CBP; CREB-binding protein |
其它 | 該抗體可檢測內源蛋白 |
蛋白質(zhì)ID | Q92793 |
目標條帶分子量(KD) | 265 |
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